Game: Hell's Hospital
Two fat guys are about to have a heart attack, but only one can be saved. This is a two player game where the objective is to beat the other guy to the operation room to save yourself at the cost of the other player.
More the Merrier: The game is a competitive or cooperative multiplayer "party game" (i.e., based on minigames, humor, 4+ players, audience engagement, etc.), meant for one screen or more.